Activation of Insect Phenoloxidase after Injury: Endogenous versus Foreign Elicitors

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Role and Importance of Phenoloxidase in Insect Hemostasis

In response to microbial infection, insects mount several defense reactions including the induction of proteolytic cascades that lead to localized melanization and coagulation. Melanization requires the activation of prophenoloxidase (proPO) to its active form phenoloxidase (PO), a key enzyme that leads to the formation of melanin at wound sites and around intruding microorganisms in the hemoly...

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Role and importance of phenoloxidase in insect hemostasis.

In response to microbial infection, insects mount several defense reactions including the induction of proteolytic cascades that lead to localized melanization and coagulation. Melanization requires the activation of prophenoloxidase (proPO) to its active form phenoloxidase (PO), a key enzyme that leads to the formation of melanin at wound sites and around intruding microorganisms in the hemoly...

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Role and Importance of Phenoloxidase in Insect Hemostasis

In response to microbial infection, insects mount several defense reactions including the induction of proteolytic cascades that lead to localized melanization and coagulation. Melanization requires the activation of prophenoloxidase (proPO) to its active form phenoloxidase (PO), a key enzyme that leads to the formation of melanin at wound sites and around intruding microorganisms in the hemoly...

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Role and Importance of Phenoloxidase in Insect Hemostasis

In response to microbial infection, insects mount several defense reactions including the induction of proteolytic cascades that lead to localized melanization and coagulation. Melanization requires the activation of prophenoloxidase (proPO) to its active form phenoloxidase (PO), a key enzyme that leads to the formation of melanin at wound sites and around intruding microorganisms in the hemoly...

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Molecular control of phenoloxidase-induced melanin synthesis in an insect.

The melanization reaction induced by activated phenoloxidase in arthropods must be tightly controlled because of excessive formation of quinones and excessive systemic melanization damage to the hosts. However, the molecular mechanism by which phenoloxidase-induced melanin synthesis is regulated in vivo is largely unknown. It is known that the Spätzle-processing enzyme is a key enzyme in the pr...

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ژورنال

عنوان ژورنال: Journal of Innate Immunity

سال: 2009

ISSN: 1662-8128,1662-811X

DOI: 10.1159/000168009